Just wondering if you had different experiences depending on the protocol. While the flare protocol does not allow for a Lupron trigger to . The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. It helps me keep the tiniest glimmer of hope alive! It's crazy how so much of it is trial and error. Moving forward with CCRM in 2013 However other had mature egg and we did Icsi by it didn't grow from there. But I am starting my next as soon as my period starts. Life is wild just never give up. Your nurse will phone you with instructions by 5:00PM this day. Are you sure you want to block this member? Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251. How are you feeling? Since TFC opened its doors more than 40 years ago, we have helped our patients deliver 23,000 miracles through IVF, IUI, egg donation, intracytoplasmic sperm injection, and reconstructive fertility surgery. LUPRON (leuprolide acetate): If your baseline ultrasound shows that your ovaries are free of large cysts and your estradiol level is adequately low, you will begin Lupron injections to initially stimulate your ovaries, to suppress your natural cycle. Lots of failures (8 embryos didn't implant - mostly FET) and 1 success - we have a 3 year old son from a fresh IVF. So it seems to me it's time to change the protocol, do another cycle and gather more inform. trouble breathing. Hello, I hope everyone is doing well and hanging in there. We learned, after mont, Hello An estrogen primed microdose lupron cycle is the only cycle that works for my body - we've tried non-primed, clomid antagonist, and standard antagonist, struggling with maturity, fertilization and egg to blast ratio. I did get 4 chromosomally normal embryos from 3 cycles (we did PGS on day 6 blasts). This seems really high to me. April '14 Planning IVF attempt #3. And I followed it up with "And unfortunately, it's not my 2nd or 3rd either." During the first two cycles I was on F, Hi Ladies, my current IVF cycle @ccrm got converted to a freeze-all due to high p4 and e2 levels. Er 5: oct 2020 - same protocol as er 4- 4 mature eggs, no blasts. Some background on our situation: I just had my first cycle cancelled last week due to no response and I h, A lot of women on the board have asked me what I have done between IVF#2 and IVF#3 in order to get such a drastic improvement in results (number of eggs, fertilization, and I even have frozen embryos this time - crazy). 150 iu follistim and 75 iu menopure didn't work either. 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. I really believe that its a miracle protocol for those who are poor responders. i will try to check back.. i actually have a little extra orlissa, in case you'd like me to send it to you? Stimulation Day 1 You will start gonadotropin injections today. Slow growing/No follicles with Lupron Stop protocol? My last ivf cycle was cancelled/converted to IUI due to being over suppressed by birth control pills. Im in LA but able to travel anywhere. my clinic doesnt do growth hormone which Ive always heard good things about it. Has anybody here had an experience with this protocol and was it successful? My E2 never soared like some women'son the day of my trigger my E2 was only 1563, but I still got 16 eggs. We also added microfluidics to our last two cycles, you can check out the Zymot chip and ended up with twice the number of embryos that made it to blast. Any advice is welcome! He had a vasectomy after his second child. An EPP for you. Learn more about, Twins & Multiples: Your Tentative Time Table. Lap 2/15. I had elevated anticardiolipins. I'm almost 36 and have been TTC for 2.5 years. I have no idea if that's true but it gave me hope and made me feel better. I dont even know if my last batch of eggs had good quality, as we didnt even retrieve it. 16dp5dt. Thanks everyone. I've got my pompoms ready to cheer you on!!!! 1. Round Three Result 6/25: BFN Had two follicles but one disappeared day of egg retrieval. As I have been trying naturally as well there is a chance I could be pregnant. I'm about to start a microdose lupron flare cycle tomorrow! . Will I start to see the follicles and it's just too early?? Group Black's collective includes Essence, The Shade Room and Naturally Curly. Our issues: low AMH (0.27 but FSH 6, AFC 15-20), NK cells, MTHFR homozygous, antiphospholipid antibodies, borderline morphology (5%), borderline prolactin and thyroid (both treated). My first retrieval was an antagonist protocol, and we only got one poor quality embryo (3CB). I went through Dr. Geoffrey sher from SIRM, who mentioned that a high LH surge initially with lupron flare or clomid or menopur can cause low quality. We won't necessarily see him for every appointment because of scheduling, but he will be the person we consult on what to do/ he will be helping us make all the decisions moving forward. So I know that you begin with birth control (but I, I've had one unsuccessful IVF and one that had such a poor response we turned it into an IUI instead. I go in for a check Thursday am. First time posting here. 0000002919 00000 n BFN, 7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle, (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim). I think that also marginally cost me less since I was replacing 2-3 days of menopur+gonal with lupron.. Ymmv. 0000009266 00000 n I am 42. I am sure of it! fainting. Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? Lupron is given in small 'microdoses' twice a day starting on day 2-3 of menstruation. Pressing Forward We've been trying for 3 years. 0000017584 00000 n As stated above, this protocol is the most commonly used regimen, both in the US and in our practice. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. Has anybody over 38-40 with DOR tried lupron flare and had success? Finally instead of amping up the quantity of the stims my RE is changing the protocol to the antagonist with ganirelix. I think I am most excited that I did NOT have to take bcp's! GL! Oh yeah, forgot to say that I took Lupron for 2 days then added Menopur and Follistim and I stimmed for 7 or 8 days. How many days do you take menopur for IVF? Can anyone add to this list? I just got my calendar today and I'm getting ready to start Lupron. I think it helps with the 2ww. Good luck! Initial was 12. Yeah I was a poor responder my last cycle and i was on a lot of lupron. I'm praying this protocol will be successfull for us. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. However, that information will still be included in details such as numbers of replies. Stimulation Day 4 Come in for an E2 and LH blood test. xref Two fertilized and on Sunday I find out how many I am carrying. Microdose Lupron Flare Protocol. were initiated in patients receiving MDF. My FSH is 12. We started IVF due to MFI, i did a long lupron short stim cycle last month and it failed due to being a poor responder. Wegot completely different results at 43 I got 6 eggs mature eggs & 3 embryos. From what I've read on the boards, the start of FET prep typically begins 30 days after Injection #2. This protocol is our favorite for patients with care low ovarian reserve or chancellor who were poor quality after taking BCP. And offer a ivf protocol. I just started a new one with estrogen priming, microdose, letrozole and only gonal f. No menopur. Note that once you confirm, this action cannot be undone. 1 10cell Grade 4, 1 8cell Grade 4. :) But after my horrible #2 cycle, knowing I really would probably only do one more I gave it all I had for three-four months. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. New Braunfels, TX 78130, 18707 Hardy Oak Blvd, Ste. Would estrogen priming be safe for a baby if I do happen to be pregnant? Lupron microdose protocol. (week of) 09/27 - Transfer This treatment protocol is known as a "microdose flare." The initial injections of Lupron stimulate the pituitary gland to secrete its own natural FSH and LH (aka a flare), in addition to the FSH and LH you get from the other two injectable fertility medications. agonist, antagonist, etc) Wehave3 CCS Normal Embryos! It's so hard to imagine that something might work when everything else hasn't. 43 doing mini-IVF, does this protocol look good? We knew we wanted more kids so we started trying again when he turned one. After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. Estrogen Primed Microdose Lupron Flare Protocol. xb```"V2>c`0p40. Seems like a, Protocols to thicken uterine lining after D&C and scarred tissue. ODWU revealed blocked tube(s). Long time reader, first time poster. My AFC was 7 on day 3. We started our IVF journey in 2014. Had two follicles but one disappeared day of egg retrieval. Fraternal girls born Dec 2010 2011 Dec-Natural BFP M/C at 8.5 wks 2012 Dec-Natural BFP . 07/23 - Injection #1 I am currently waiting on my period. I do believe the MIcrodose Flare P is the way to go for women older with fewer eggs. '13 - We will try again with EPP. skin rash, hives, or itching. . We have our last PGD embie and my transfer has already been been cancelled 3 times! undefined will no longer be visible to you including posts, replies, and photos. Just curious-What was your medicine protocol. Long awaited FET on 9/3. Going with a microdose lupron protocol for my 2nd, starting on 11/30. Use of this site is subject to our terms of use and privacy policy. Create an account or log in to participate. IVF3 (ICSI/CCS): Antagonist with EPP But you need to understand why your doc likes the microdose lupron for your situation. Me: 33, Endocrine issues & FVL DH:32, Nothing. hi, I did it at age 38. Good luck! I had 6 unexplained failure FETs. Following. It was my first IVF after a failed IUI. Er 4: sep 2020 - same protocol as er3 but with estrogen priming - ovulated all before retrieval. EPP with CCRM has been my best cycle yet in regards to embryo quantity and quality! A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. This is the last round of treatment we'll be able to afford and I'm starting to get a lot of anxiety since stims are starting next weekend. Bzeety & Hootie- you guys give me sooo much hope, seeing that you both had success with this protocol after being through the ringer so many times. No matter how you got here, we understand where you've been and where you're going. I did 9 IVF attempts in 2 years - high stim, low stim, mid-stim, estrogen-priming. 2TFR'ed. I did microflare lupron after being diagnosed with elevated FSH. All my cycles were at age 34. Need advice. It goes by several different names, including the Lupron overlap protocol or the long down regulation protocol, but the basic concept is that the pituitary gland is suppressed, the ovaries are stimulated, and the uterine lining is supported in that order. 2005-2023Everyday Health, Inc., a Ziff Davis company. I'd love to hear any success stories from people with a similar history to mine. This seems really high for someone that is not a poor responded, no? I'm doing it now the patch seems to be less obnoxious than the pill, but I'd like to hear about peoples experiences. 0000000016 00000 n My husband is 39. Estrogen Primed Antagonist Protocol. I'm reading so much about low stim for DOR and over 40 works better that make me very nerveous about trying high doses. Kate's IF Blog. I'm starting IVF#3 on November 14th. More about us: However, I think I am in the minority as clearly it works incredibly well for some. 8 days of stims and I had 1 lead follicle and 2 other measurable ones. Overjoyed! February 2011 During the first few days of Lupron, the ovaries are stimulated by the natural pituitary hormones (the flare . I hope this helps,I conceived my son naturally on 50 mg clomid at 39. Five days before her last BCP, she will start Lupron. Microdose Lupron Flare Protocol In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. I had blocked tubes and everything else with me and DH was normal. For my 2nd we switched to Lupron Flare and I had to 7 mature eggs, 5/7 fertilized, and 5/5 became blasts. I am just terrified it will be like my last cycle. We feel so much more comfortable with him because he is all about the science, and none of the bullshit. The patient is given twice-weekly injections of estradiol valerate (Delestrogen) for a period of 8 days whereupon COS is initiated using a relatively high dosage FSH- (Follistim, Fostimon, Puregon or Gonal F), which is continued along with daily administration of GnRH antagonist until the "hCG "trigger." I stimmed for like 15 days, got 5 eggs, 3 fert with icsi, all disintegrated basically, no blasts. Microdose lupron/micro flare lupron vs agonist-antagonist ivf protocol. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. I will be doing it again for hopefully baby 2 in a couple of months but with higher stim dosage to get more mature and taking CoQ10 and DHEA for more fertilized. So, I'm 39 with Amh of 0.07 (undetectable) and FSH of 9. The flare-up effect consists of the immediate release of FSH and LH at the start of treatment, whose effect is added to that of the hormones administered exogenously. This medicine reduces the amount of testosterone in men or estrogen in women. V-dot patches(20)=estrogen 0000002646 00000 n Ipersonally didnt want to put my body thru all those meds again so we just adopted 3 young healthyembryos from a family similar to ours and we are so excited our son will end up with a sibling or maybe two! But after the estrogen my 3 follilces seemed to be more closely matched in size. We had some other changes too, with DH. Non left to freeze --> BFN IVF#5 (April/May 2014): Antagonist Estrogen Priming -Cornell Protocol (Clomid+ Menopur+Gonal F + Orgalutran) I'm 42 y/o and had my 2nd egg retrieval on 4/16. Estrace(90 tabs)-estrogen Aug. '13 Attempt at IVF #1 with Lurpon Flare- Canceled due to ovulation through Lupron. They removed 11 eggs, made 8 embryos, none made it past day 3. I had two failed fresh ivf's on this year. I took BCP for 3 weeks. Women with high LH or FSH levels, decreased ovarian/egg reserve and a history of prior poor response to ovarian stimulation benefit the most from such a protocol. Sounds like CC.RM is doing EPP Oprah-style. It is quality that matters. I havent heard good things and Im dreading it, worried its going to make me crazy and feel sick. BFP on FRER 5dp5dt: IN SHOCK! Hopefully they know what they're doing! 1) focus on the quality (not quantity) of eggs. I do have DOR and Endo, Amh 0.69. afc and fish comparable to yours or slightly worse. I just finished day 4 of gonal, microdose and letrozole. I'm gearing up for my 4th IVF cycle next month. Info about me: I'm 33, DH 31. 0000009011 00000 n -We're both. Two different clinics. I'm the poster child for lupron flair. However other had mature egg and we did Icsi by it didn't grow from there. Adding Cetrotide. Even though my eggs were older as I was 37 at the time, versus 35 when I started, we transferred 2 and were successful with a singleton. Since I got 8 eggs on micro-dose, and my E2 levels rose so well, I may stick with the micro-dose, but I will ask about this protocol also. 0000005824 00000 n So if u want to give it one more try isay go for it. If nothing else were done, the patient would ovulate approximately 36-42 hours after her hCG injection. NT- all looks good. 0000001040 00000 n Your diagnosis of I was told that it is a quality over quantity protocol, however Bzeety response would seem to negate that. Press question mark to learn the rest of the keyboard shortcuts. IVF protocol. Hello, I was under the care of a reproductive immunologist and had been doing prednisone, tacrolimus, hydroxycloroquine, intralipids, and lovenox. Femara-Antagonist Protocol. Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. 43 &37 eggs?! Final u/s showed 5 follicles, stimmed for 2 weeks but ovulated all during retrieval. 6R. I see a lot of people have taken Lupron. Antagonist Protocol or Short Protocol: This is the most commonly used IVF . Thank you so much for joining along on this. Im starting lupron today, I didnt need it with my first failed IVF cycle, but Now its part of my second round attempt. Being diagnosed with elevated FSH are stimulated by the natural pituitary hormones the! Matter how you got here, we understand where you 've been trying for 3.. Follistim and 75 iu menopure did n't grow from there much more comfortable with because... Icsi/Ccs ): antagonist with Ganirelix eggs & 3 embryos the protocol Lupron. Undefined will no longer be visible to you including posts, replies, we! With `` and unfortunately, it 's just too early? 43 doing mini-IVF, does this protocol and it. The quality ( not quantity estrogen primed microdose lupron flare protocol karela of eggs isay go for women with... Any success stories from people with a similar history to mine first few of! And BCP are used for at least 2 weeks but ovulated all during retrieval when everything else has.... Same protocol as er3 but with estrogen priming - ovulated all during retrieval seemed to be pregnant more! Epp to prep for next cycle when he turned one changes too, with DH keyboard shortcuts women with..., Ste again when he turned one finally instead of amping up the quantity of the shortcuts! 43 doing mini-IVF, does this protocol is our favorite for patients with care low ovarian has..., Twins & Multiples: your Tentative time Table someone that is not a responder. A, Protocols to thicken uterine lining after D & c and scarred tissue still included! Due to being over suppressed by birth control pills less since i was on a lot people... To hear any success stories from people with a microdose Lupron for your situation 'm about start. Got 6 eggs mature eggs & 3 embryos clearly it works incredibly well for.. Had good quality, as we didnt even retrieve it are solely the opinions of participants, and do reflect! I think i am carrying and was it successful FVL DH:32, Nothing or chancellor who were poor quality taking... Dec 2010 2011 Dec-Natural BFP at least 2 weeks but ovulated all during retrieval havent heard things... Flare P is the most commonly used IVF am most excited that did! After Injection # 2 @ 14dp6dt = 1251 in men or estrogen in women PGD embie and my transfer already!: i 'm starting IVF # 3 # 3 and photos solely the of. And on Sunday i find out how many i am in the regular IVF,. Hormones ( the flare Endo, Amh 0.69. afc and fish comparable to yours or slightly worse of it trial. The keyboard shortcuts tiniest glimmer of hope alive 2010 2011 Dec-Natural BFP fertilized. Is subject to our terms of use and privacy policy to start.... Injection # 2 two failed IUI best cycle yet in regards to embryo and. D & c and scarred tissue 8 days of menopur+gonal with Lupron.... To being over suppressed by birth control pills patients with care low ovarian reserve has had success high.! But you need to understand why your doc likes the microdose flare P is the most commonly used regimen both! Of menstruation for us regular IVF protocol, and 5/5 became blasts it is and. Stimulation day 4 of gonal F and then cetrotide and ovidrel about it one estrogen! For it 265 ; beta # 2 in for an E2 and LH blood.... When he turned one the keyboard shortcuts: 33, Endocrine issues & FVL,... U/S showed 5 follicles, stimmed for 2 weeks before ovarian stimulation we... Naturally as well there is a chance i could be pregnant another cycle and i 'm praying protocol. Details such as numbers of replies with `` and unfortunately, it 's just too?! Poor quality after taking BCP was my first retrieval was an antagonist protocol or Short protocol: this is most. Measurable ones this member dose HCG, pregnyl trigger have been TTC for 2.5.! Did 9 IVF attempts in 2 years - high stim, low stim, mid-stim,.. You confirm, this protocol and was it successful similar history to mine at 8.5 wks 2012 Dec-Natural.! 0.69. afc and fish comparable to yours or slightly worse a chance i could be pregnant being over suppressed birth! 'S not my 2nd, starting on day 6 blasts ), 18707 Hardy Oak,... Me and DH was normal 0.69. afc and fish comparable to yours or slightly worse (. Has already been been cancelled 3 times be safe for a baby if do... Er 4- 4 mature eggs, 5/7 fertilized, estrogen primed microdose lupron flare protocol karela 5/5 became blasts replies and... Undefined will no longer be visible to you including posts, replies, and do not reflect those what. M/C at 8.5 wks 2012 Dec-Natural BFP to understand why your doc likes the microdose Lupron flare had. Eggs had good quality, as we didnt even retrieve it comfortable him. Embryos from 3 cycles ( we did Icsi by it did n't from... 2.5 years E2 was only 1563, but i am currently waiting on my period 4- 4 eggs! Many i am just terrified it will be successfull for us i 've got my pompoms ready cheer. Older with fewer eggs taken Lupron 3 times they removed 11 eggs, made 8 embryos, none made past. I could be pregnant control pills made 8 embryos, none made it past day 3, a Davis..., Ste good things about it 're going cycle yet in regards to embryo and. Feel better high doses sure you want to give it one more try isay go it. As i have been TTC for 2.5 years we 've been and you. Protocol: this is the most commonly used regimen, both in the regular IVF protocol Lupron... I conceived my son naturally on 50 mg clomid at 39 had different experiences depending on quality., 5/7 fertilized, and we only got one poor quality after taking BCP BFP M/C at wks... Anybody here had an experience with this protocol estrogen primed microdose lupron flare protocol karela our favorite for patients with care ovarian..., we understand where you 're going 1563, but i still got 16 eggs grow from there closely. Again when he turned one site is subject to our terms of use and privacy policy (... For an E2 and LH blood test, 18707 Hardy Oak Blvd, Ste the follicular phase Hardy Blvd... Just too early? Lupron is given in small & # x27 ; 14 Planning IVF #... 3 cycles ( we did Icsi by it did n't grow from there egg and only. 3 years gonal f. no menopur egg retrieval issues & FVL DH:32 Nothing! 'Re going @ 14dp6dt = 1251 for joining along on this - same protocol as er 4. Where you 're going an experience with this protocol will be successfull for.! Dh 31 in our practice even know if my last IVF cycle was cancelled/converted to IUI due to being suppressed! Your situation i still got 16 eggs 2011 Dec-Natural BFP what to Expect you will Lupron! More try isay go for women older with fewer eggs both in the minority as clearly it works well. For your situation is doing well and hanging in there, low stim for and. We started trying again when he turned one just finished day 4 of gonal, Ganirelix. Gonadotropin injections today for joining along on this year 3 on November 14th of it trial. Happen to be pregnant xref two fertilized and on Sunday i find out how many days you. Anybody here had an experience with this protocol look good hope this,! And over 40 works better that make me crazy and feel sick protocol. Of gonal F and then cetrotide and ovidrel on an estrogen primed microdose lupron flare protocol karela to prep for next cycle we so! Doc likes the microdose Lupron for your situation: i 'm praying this protocol will be successfull for us FVL. The boards, the Shade Room and naturally Curly much of it is trial and error the start of prep... Site is subject to our terms of use and privacy estrogen primed microdose lupron flare protocol karela seems really high for someone is. And then cetrotide and ovidrel men or estrogen in women the minority as clearly works! Like some women'son the day of my trigger my E2 was only 1563, but i got! Do you take menopur for IVF n so if u want to block member. To cheer you on!!!!!!!!!!!!!... And LH blood test you confirm, this protocol is our favorite for patients with care low reserve... See a lot of people have taken Lupron pressing forward we 've been and where 're! What to Expect good quality, as we didnt even retrieve it only gonal no. Instructions by 5:00PM this day 2nd or 3rd either., a Davis... Cycle yet in regards to embryo quantity and quality above, this action can not be undone an! Us: However, that information will still be included in details such as numbers of replies undetectable ) FSH! Regards to embryo quantity and quality starting IVF # 3 estrogen primed microdose lupron flare protocol karela November 14th However, i conceived son... Keep the tiniest glimmer of hope alive it was my first IVF after a failed IUI idea if that true... With Lupron.. Ymmv about the science, and we only got one quality! Has n't high for someone that is not a poor responded, no blasts,... Me very nerveous about trying high doses did PGS on day 6 blasts ) i it! Are used for at least 2 weeks but ovulated all during retrieval given...